Cibinetide Peptide for Sale – Direct from Shanghai Manufacturer

Cibinetide (ARA-290) represents a breakthrough in peptide therapeutics, offering researchers a highly selective tool for investigating tissue protection and repair without the complications associated with full-length erythropoietin (EPO). As an 11- to 15-amino acid synthetic peptide derived from the Helix-B surface region of EPO, cibinetide is engineered to activate the innate repair receptor (IRR) while completely bypassing the classical EPO receptor that drives red blood cell production.

If you are searching for “cibinetide peptide for sale” for your laboratory investigations, you need a manufacturing partner who understands the complexity of this innovative peptide and can deliver the purity your studies demand. That partner is ShanghaiA Peptides.

We are a legitimate, licensed manufacturer operating from our headquarters at No. B Room 326, Jinhai Road 2588, Pudong District, Shanghai, China. Our facility is dedicated to the research, development, and production of high-purity peptide raw materials, catalog peptides, fluorescent dyes, and amino acids. When you purchase this product from ShanghaiA Peptides, you are buying directly from the source—not a middleman or reseller.

Understanding Cibinetide: The Selective Innate Repair Receptor Activator

It is a synthetic peptide whose sequence is inspired by the tissue-protective domain of human erythropoietin (EPO). Unlike EPO, which stimulates both tissue repair and red blood cell production, cibinetide was specifically designed to isolate only the cytoprotective functions, offering researchers a way to study tissue repair mechanisms without the confounding effects of erythropoiesis.

Key Characteristics

Parameter	Specification
Sequence	Glp-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser
Molecular Formula	C₅₁H₈₄N₁₆O₂₁
Molecular Weight	Approximately 1257.3 g/mol
CAS Number	1208243-50-8
Form	Lyophilized powder
Purity	≥99% (verified by HPLC)
Storage	-20°C, protected from light and moisture

Mechanism of Action: The Innate Repair Receptor (IRR)

The scientific basis for cibinetide’s selectivity lies in its interaction with a specific receptor complex. The innate repair receptor (IRR) is a heteromeric complex formed by the erythropoietin receptor (EPOR) and the β-common receptor (CD131). This receptor is expressed on many cell types, including nerve cells, immune cells, and cardiomyocytes, and is upregulated following tissue injury.

Receptor Target	Activation Effect	Research Implications
Innate Repair Receptor (EPOR/βcR)	Activates tissue-protective and anti-inflammatory pathways	Studies neuroprotection, wound healing, and tissue regeneration
Classical EPOR Homodimer	Does NOT bind	Prevents stimulation of red blood cell production

When cibinetide binds to the IRR, it triggers intracellular signaling cascades primarily via JAK2/STAT, PI3K/Akt, and NF-κB pathways that reduce inflammatory signaling, limit apoptosis, and support tissue repair.

Why Cibinetide Matters in Research

Cibinetide has emerged as a critical research tool across multiple domains, with studies demonstrating its potential to reduce inflammation, protect nerve tissue, and promote healing without the safety concerns of full-length EPO.

Key Research Applications

Research Area	Key Findings
Neuropathic Pain & Small Fiber Neuropathy	Supports nerve regeneration and improves nerve fiber density
Cardiovascular Aging	Helps preserve cardiac function and reduce inflammation
Inflammation & Cytokine Modulation	Suppresses TNF-α and IL-6 signaling
Mitochondrial Health	Enhances autophagy and reduces oxidative stress
Wound Healing & Tissue Repair	Supports endothelial survival and tissue regeneration
Autoimmune & Inflammatory Diseases	Investigated in inflammatory disease models

The Critical Importance of Quality for Cibinetide Research

When you purchase it, quality parameters are non-negotiable. It is a complex peptide requiring precise synthesis to ensure correct sequence and purity for reliable research results.

The ShanghaiA Peptides Quality Standard

• 99% Purity Guarantee verified by HPLC
• Mass Spectrometry molecular weight confirmation
• Amino Acid Analysis sequence verification
• Endotoxin Testing available for sensitive applications
• Batch-specific Certificates of Analysis (COAs)
• Stability Testing for transport and storage integrity

The Manufacturer Advantage: Why Source this peptide from ShanghaiA Peptides

When you search for “cibinetide peptide for sale,” you encounter many options. Here is why direct sourcing from our Shanghai facility is the superior choice.

Complete Transparency

• Physical manufacturing location in Pudong District, Shanghai
• Decades of peptide synthesis expertise
• Direct manufacturer pricing with no reseller markups

Technical Expertise

Our team understands the unique requirements of cibinetide research, including:

• Sequence integrity for IRR selectivity
• Proper storage and handling
• Reconstitution recommendations
• Research compliance documentation
• EPO biology and IRR signaling pathways

Seamless Supply to the Australia Market

Sourcing cibinetide peptide for sale from China should be straightforward. We have optimized our logistics specifically for Australian researchers and wholesale partners.

• Fast shipping to Australia
• Cold-chain packaging for peptide stability
• Moisture-resistant sealed packaging
• Wholesale support programs
• Customs documentation assistance
• Real-time shipment tracking

Frequently Asked Questions

What exactly is cibinetide peptide?

It is a synthetic peptide derived from the tissue-protective domain of erythropoietin (EPO). It selectively activates the innate repair receptor (IRR) without stimulating red blood cell production.

What purity levels do you guarantee?

We guarantee ≥99% purity verified through HPLC testing with batch-specific COAs.

What is the CAS number for cibinetide?

1208243-50-8.

Is your cibinetide for human consumption?

No. Our cibinetide is strictly supplied for laboratory research purposes only and is not intended for human or veterinary use.

How should cibinetide be stored?

Store at -20°C protected from light and moisture. Avoid repeated freeze-thaw cycles.

Quality Control: The ShanghaiA Peptides Standard

Every batch undergoes strict analytical testing, including:

• HPLC purity analysis
• Mass spectrometry confirmation
• Amino acid sequence verification
• Endotoxin testing
• Stability testing

Each shipment includes full documentation with Certificates of Analysis, batch traceability, and storage recommendations.

Beyond Cibinetide: Your Complete Research Partner

ShanghaiA Peptides is more than just a supplier of this peptide for sale. We are a full-service biochemical manufacturer supporting research worldwide.

Our Capabilities

• Custom peptide synthesis
• Catalog research peptides
• Neuroprotective peptide libraries
• Fluorescent dyes
• Research-grade amino acids

Conclusion

The search for premium cibinetide peptide for sale ends with ShanghaiA Peptides. As a dedicated manufacturer of research peptides and biochemical materials, we combine manufacturing expertise, strict quality standards, and reliable international logistics to support laboratories and research institutions across Australia and worldwide.

Whether your research focuses on neuropathic pain, cardiovascular aging, tissue repair, or inflammatory signaling, ShanghaiA Peptides delivers the high-purity cibinetide required for reliable and reproducible laboratory investigations.