Description
KPV Peptide for Sale – Direct from Shanghai Manufacturer
KPV (Lys-Pro-Val) represents a significant advancement in anti-inflammatory research. As the C-terminal tripeptide fragment of alpha-melanocyte stimulating hormone (α-MSH), this potent 3-amino acid peptide offers researchers a powerful tool for investigating inflammation modulation, immune regulation, and tissue protection without the melanotropic side effects of the parent hormone. If you are searching for “KPV peptide for sale” for your laboratory investigations, you need a manufacturing partner who understands the complexity of this small but mighty tripeptide and can deliver the purity your studies demand. That partner is Shanghai Apeptides Co., Ltd.
We are a legitimate, licensed manufacturer operating from our headquarters at No. B Room 326, Jinhai Road 2588, Pudong District, Shanghai, China. Our facility is dedicated to the research, development, and production of high-purity peptide raw materials, catalog peptides, fluorescent dyes, and amino acids. When you purchase KPV peptide for sale from shanghaiapeptides.com, you are buying directly from the source—not a middleman or reseller.
Understanding KPV: The Tripeptide Powerhouse
KPV is a synthetic tripeptide with the sequence Lys-Pro-Val, representing the C-terminal end of alpha-melanocyte stimulating hormone (α-MSH). Despite its small size—only three amino acids—KPV retains the potent anti-inflammatory and immunomodulatory properties of the full-length α-MSH molecule without its melanotropic (pigmentation-inducing) effects.
Key Characteristics
| Parameter | Specification |
|---|---|
| Sequence | H-Lys-Pro-Val-OH (Lysine-Proline-Valine) |
| Molecular Formula | C₁₆H₃₁N₅O₄ |
| Molecular Weight | Approximately 357.45 g/mol |
| CAS Number | 67727-97-3 |
| Form | Lyophilized powder |
| Purity | ≥99% (verified by HPLC) |
| Storage | -20°C, protected from light and moisture |
Mechanism of Action: Potent Anti-Inflammatory Signaling
KPV exerts its effects through multiple interconnected pathways that converge on the master inflammatory regulator NF-κB.
| Pathway | Mechanism | Research Implications |
|---|---|---|
| NF-κB Inhibition | Stabilizes IκB-α, preventing p65RelA nuclear translocation | Studies inflammation regulation |
| Cytokine Suppression | Reduces TNF-α, IL-1β, IL-6, and IL-8 | Investigates inflammatory cascade modulation |
| PepT1 Transport | Enters cells via oligopeptide transporter PepT1 | Cellular uptake and bioavailability studies |
| Cell Migration | Promotes keratinocyte and fibroblast migration | Wound healing and tissue repair research |
| Antioxidant Activity | Reduces oxidative stress markers | Cellular protection studies |
Why KPV Matters in Research
KPV has emerged as a critical research tool across multiple inflammatory and immune-related domains. Unlike full-length α-MSH, which can cause pigmentation, KPV offers targeted anti-inflammatory effects without off-target melanocortin receptor activation.
Key Research Applications
| Research Area | Key Findings | Research Context |
|---|---|---|
| Inflammatory Bowel Disease (IBD) | Reduces disease activity and inflammatory markers | Crohn’s disease and ulcerative colitis research |
| Wound Healing | Accelerates wound closure and reduces inflammation | Burn healing and diabetic ulcer models |
| Contact Dermatitis | Reduces inflammatory cell infiltration | Dermatological inflammation studies |
| Acute Pancreatitis | Ameliorates pancreatic inflammation | Acute injury and inflammation research |
| Cellular Uptake Studies | PepT1-mediated intracellular transport | Drug delivery and uptake investigations |
| Sepsis & Systemic Inflammation | Suppresses pro-inflammatory cytokines | Systemic inflammatory response studies |
Distinctive Research Advantages
- NF-κB Specificity with nanomolar potency
- No melanotropic or pigmentation-inducing effects
- Intracellular activity through PepT1 transport
- Multi-system efficacy across gastrointestinal, dermatological, and inflammatory models
The Critical Importance of Quality for KPV Research
When you purchase KPV peptide for sale, quality parameters are non-negotiable. KPV is a short tripeptide requiring precise synthesis to ensure correct sequence, purity, and stability for reliable research outcomes.
The Shanghai Apeptides Quality Standard
- 99% Purity Guarantee verified by HPLC
- Mass spectrometry molecular weight confirmation
- Amino acid sequence verification
- Accurate peptide content analysis
- Counterion analysis provided
- Water content ≤8.0%
- Endotoxin testing available
- Batch-specific Certificates of Analysis (COAs)
- Stability testing for long-term integrity
The Manufacturer Advantage: Why Source KPV from Shanghai Apeptides
When you search for “KPV peptide for sale,” you encounter many suppliers. Here is why direct sourcing from our Shanghai facility is the superior choice.
Complete Transparency
- Physical facility in Pudong District, Shanghai
- Experienced peptide synthesis specialists
- Direct manufacturer pricing without reseller markups
Technical Expertise
Our team understands:
- PepT1 transporter studies
- Peptide stability and storage requirements
- Proper reconstitution procedures
- NF-κB pathway modulation research
- Documentation and compliance requirements
Quality You Can Trust
- Rigorous HPLC and MS testing
- Full batch traceability
- Consistent purity and manufacturing standards
Seamless Supply to the Australian Market
Sourcing KPV peptide for sale from China should be simple and reliable. We have optimized our logistics specifically for Australian researchers and wholesale partners.
- Fast shipping to Australia
- Temperature-controlled cold-chain packaging
- Moisture-protected double-sealed packaging
- Wholesale support for Australian supply companies
- Customs documentation assistance
- Real-time shipment tracking
Research Applications: Where KPV Excels
Inflammatory Bowel Disease Research
- DSS and TNBS colitis models
- Histological inflammation scoring
- Cytokine and MPO analysis
- Disease activity investigations
Wound Healing Research
- Keratinocyte migration assays
- Fibroblast proliferation studies
- Excisional wound healing models
- Inflammatory resolution studies
Dermatitis Research
- Contact hypersensitivity models
- Skin inflammation analysis
- Cytokine quantification studies
Acute Pancreatitis Research
- Pancreatic edema and necrosis studies
- Cytokine marker investigations
- Survival outcome analysis
Cellular Transport Research
- PepT1 transporter assays
- Intracellular peptide localization
- Structure-activity relationship studies
Frequently Asked Questions
What exactly is KPV peptide for sale at Shanghai Apeptides?
KPV is a synthetic tripeptide corresponding to the C-terminal fragment of α-MSH. It retains potent anti-inflammatory properties without melanotropic effects and is intended strictly for laboratory research use only.
What purity levels do you guarantee?
We guarantee ≥99% purity verified through HPLC testing, with batch-specific COAs available.
What is the CAS number for KPV?
CAS Number: 67727-97-3
What is the molecular weight of KPV?
Approximately 357.45 g/mol.
Is your KPV for human consumption?
No. Our KPV is strictly for research and laboratory use only and not intended for human or veterinary applications.
How should KPV be stored?
Store at -20°C, protected from light and moisture.
Do you ship across Australia?
Yes. We supply research institutions, laboratories, and wholesale partners throughout Australia.
Can you support wholesale orders?
Absolutely. We offer competitive wholesale pricing for Australian distributors and research suppliers.
Quality Control: The Shanghai Apeptides Standard
Every KPV batch undergoes:
- HPLC purity analysis
- Mass spectrometry verification
- Amino acid sequence analysis
- Peptide content determination
- Water and counterion analysis
- Stability testing
- Batch-specific documentation
Beyond KPV: Your Complete Research Partner
Shanghai Apeptides Co., Ltd. is more than just a supplier of KPV peptide for sale. We are a full-service peptide and biochemical manufacturer supporting advanced research worldwide.
Our Capabilities
- Custom peptide synthesis
- Catalog peptide production
- Anti-inflammatory peptide libraries
- Fluorescent dyes and labeling agents
- Amino acid manufacturing
Quality Certifications & Compliance
- Licensed peptide manufacturer in Shanghai
- Strict quality control procedures
- Transparent documentation and traceability
- Experienced scientific support team
- Research-use-only compliance standards
The Science Behind KPV
KPV (Lys-Pro-Val) was identified as the minimal active sequence of α-MSH retaining anti-inflammatory activity without melanotropic effects. Its mechanism primarily involves inhibition of NF-κB activation by stabilizing IκB-α and suppressing inflammatory cytokine transcription.
The peptide’s small size and PepT1-mediated transport make it especially valuable for cellular uptake, inflammation modulation, and drug delivery investigations.
Your Trusted Source for KPV Peptide for Sale
The search for premium KPV peptide for sale ends at Shanghai Apeptides Co., Ltd. As a dedicated peptide manufacturer, we combine scientific expertise, manufacturing precision, and strict quality control to deliver high-purity research peptides for Australian laboratories and wholesale partners.
Whether your focus is inflammatory bowel disease research, dermatology, wound healing, or advanced inflammation studies, Shanghai Apeptides is your trusted manufacturing partner.





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